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The 2nd response cycle in NO synthesis includes O2 binding to ferrous NOS to form the Fe, IIO2 intermediate, followed by oxidation of NOHA to generate ferric enzyme, NO, citrulline, and water as items (Fig. 9) - circular dichroism. As drawn in Fig - http://www.video-bookmark.com/bookmark/6114703/olis-clarity/. 9, the response may also involve electron transfer from H4B to the Fe, IIO2 intermediate

l9 As shown in Fig. 9, this might be because the H4B extreme function as an electron sink in a later point in the response, so regarding permit NOS to, Fig. 9. A design for NORA oxidation by NOSoxy in the single turnover reaction. More hints Oxygen binds to the ferrous protein to form the Fe, IIO2 species, which upon receiving an electron from H4B forms a putative hemeperoxo intermediate that responds with NOHA.